Ulcefate/Ulcefate Chewable Tablet Mechanism of Action

Pharmacology: Ulcefate/Ulcefate Chewable Tablet s a nonsystemic cytoprotective agent without inhibiting gastric acid secretion or substantially neutralizing intraluminal acid.
Site protective action: Ulcefate/Ulcefate Chewable Tablet forms a protective layer over ulcerated and non-ulcerated mucosa (more specific on ulcer).
Adsorption: Ulcefate/Ulcefate Chewable Tablet adsorbs both pepsin and bile acid.
Secretory effect: Ulcefate/Ulcefate Chewable Tablet stimulates bicarbonate and mucous secretion by the gastric mucosa.
Influence on endogenous mediators: Ulcefate/Ulcefate Chewable Tablet stimulates the synthesis and release of prostaglandin and prostacyclin.
Cellular effects: Ulcefate/Ulcefate Chewable Tablet prevents damage to the proliferative zone by necrotizing agents and Ulcefate/Ulcefate Chewable Tablet maintains the structural and functional preservation of gastric microvasculature.
Other effects: Ulcefate/Ulcefate Chewable Tablet decreases parietal cell sensitivity.